AM694

AM694
AM694
AM-694 (1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole) is a drug which actsas
a potent and selective agonist for the cannabinoid receptor CB1, with
a Ki of 0.08nM at CB1 and 18x selectivity over the related CB2 receptor.
It is unclear what is responsible for this unusually high CB1 binding 
affinity, but it makes the 18F radiolabelled derivative of AM-694 useful
for mapping the distribution of CB1 receptors in the body. 

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